Nanomaterials

For repair, ADME, imaging, testing & Health and Safety

Nanomaterials

The use of nanomaterials for the construction of molecular medical devices, diagnostics, environment control, the facilitation of repair, the removal of the unwanted, Quality control and the most important Health and Safety.

Health and safety

ADME

Subcellular ADME

Molecular Medical Device

 

Self assembled materials

Hemostasis

Stem cell niche creation

Stabilization of environment

CNS repair

 

Adaptable Materials

Self assembling materials

Disassembling materials

Warming / cooling

Protective at different temperatures

Hydrating versus dehydrating

Chelating in mining operations

Recoverable / recyclable

Manufacturing

QA/QC

Diagnostics

 

TessArae

Conjunctivitis

Gastroenteritis

 

Ellis-Behnke RG and Schneider GE. “Peptide Amphiphiles and Porous Biodegradable Scaffolds for Tissue Regeneration in the Brain and Spinal Cord.” In: Biomedical Nanotechnology, Methods in Molecular Biology series, Sarah Hurst (vol. ed.), vol. 726. New York, Springer, 2011. (In press).

 

Ling MT, Tay DKC, Cheung WH and Ellis-Behnke RG. (2011) Using self-assembled nanomaterials to delay the formation of metastatic cancer stem cell colonies while artificially mimicking a stem cell niche in vitro. Cell Transplantation 20: 127-131.

 

Ellis-Behnke RG and Jonas JB. (2011) Redefining tissue engineering for nanomedicine in ophthalmology. Acta Ophthalmol. 89: e108-14.

Liang YX, Chan KCW, Cheung SWH, Tay DKC, Wu EX and Ellis-Behnke RG. (2010) CNS regeneration after chronic injury using a self-assembled nano material and MEMRI for real-time in vivo monitoring. Nanomedicine DOI: 10.1016/j.nano.2010.12.001

 

Ellis-Behnke RG. (2010) At the nanoscale: nanohemostat, a new class of hemostatic agent. WIRE’s Nanomed Nanobiotechnol. DOI: 10.1002/wnan.110.

 

Woo PCY, Lau SKP, Choi GKY, Fung HT, Shek KC, Miao J, Chan BYL, Ng KHL, Ngan AHY, Ellis-Behnke RG, Que TL, Kam CW and Yuen KY. (2010) Resequencing microarray for detection of human adenoviruses in patients with conjunctivitis.  J Clin Virol. 47: 282-5.

 

Woo PCY, Lau SKP, Choi GKY, Fung HT, Shek KC, Miao J, Chan BYL, Ng KHL, Ngan AHY, Ellis-Behnke RG, Que TL, Kam CW and Yuen KY. (2010) Resequencing microarray for detection of human adenoviruses in patients with community-acquired gastroenteritis: a proof-of-concept study. J Med Microbiol. 47(3):282-5.

 

Cheung ACY, Yu Y, Tay DKC, Ellis-Behnke RG and Chau Y. (2010) Ultrasound-enhanced intrascleral delivery of protein. Int J Pharm. 401(1-2):16-24.

 

Ellis-Behnke RG, Liang YX, Guo J, Tay DKC, Schneider GE, Teather LA, Wu W and So KF. (2009) Forever young: how to control the elongation, differentiation and proliferation of cells using nanotechnology. Cell Transplantation 18: 1047-1058.

 

Ellenberg D, Shi J, Jain S, Chang JH, Brady S, Melhem E, Lakkis F, Adamis A, Chen DF, Ellis-Behnke RG, Langer RS, Strittmatter S and Azar DT. (2009) Impediments to eye transplantation: ocular viability following optic nerve transection or enucleation. Br J Ophthalmol. 93: 1134-1140.

 

Ye Z, Zhang H, Luo H, Wang S, Zhou Q, Du X, Tang C, Chen L, Liu J, Shi YK, Zhang EY, Ellis-Behnke RG and Zhao X. (2008) Temperature and pH effects on biophysical and morphological properties of self-assembling peptide RADA16-I. J Peptide Science 14: 152-162.

 

Ellis-Behnke RG, Teather LA, Schneider GE and So KF. (2007) Using nanotechnology to design potential therapies for CNS regeneration. Current Pharmaceutical Design 13: 2519-2528.

 

Guo J, Su H, Zeng Y, Liang YX, Ellis-Behnke RG, So KF and Wu W. (2007) Reknitting the injured spinal cord using self-assembling peptide nanofiber scaffold. Nanomedicine 3: 311-21.


 

Ellis-Behnke RG, Liang YX, You SW, Tay DKC, Zhang S, So KF and Schneider GE. (2006) Nano neuro knitting: peptide nanofiber scaffold for brain repair and axon regeneration with functional return of vision, Proc Nat Acad Sci USA 103: 5054-5059.

-- Comments in:              

 -Nature Materials – Nanozone news online (2006) Apr. 13     

-The Lancet Neurology (2006) May; 5(5): 386-387

-ACS Chemical Biology (2006) May; 1(3): 116

-Nature Reviews Neuroscience (2006) May; 7(5): 333

-Journal of the American Medical Association (2007) Jan.; 297(1): 31

-Technology Review (2007) Mar./Apr.; 110: 52-55

 

Ellis-Behnke RG, Liang YX, Tay DKC, Kau PWF, Schneider GE, Zhang S, Wu W and So KF. (2006) Nano hemostat solution: immediate hemostasis at the nanoscale. Nanomedicine 2: 207-15.

-- Comments in:              

 -Science (2006) Oct. 10; ScienceNOW daily news

-Nature Biotechnology (2006) Nov.; 24(11): 1367

-Nature Nanotechnology (2006) Dec.; 1(3): 166-167

-Nanomedicine (2006) Dec.; 2(4): 216                                    

-Journal of the American Medical Association (2007) Jan.; 297(1): 31

-Technology Review (2007) Mar./Apr.; 110(2): 52-55

 

Schneider GE, Ellis-Behnke RG, Liang YX, Kau PWF, Tay DKC and So KF. (2006) Behavioral testing and preliminary analysis of the hamster visual system. Nat Protoc.1: 1898-1905.

 

Ellis-Behnke RG, Teather LA and So KF. (2006) Molecular restoration of the body: nano neuro knitting for brain repair. J European Anti-Ageing Medicine & British Anti-Ageing Medical Journal 4: 34-35.

 

Ellis-Behnke RG, So KF and Zhang S. (2006) Molecular repair of the brain using self-assembling peptides. Chimica Oggi 24: 41-43.